Deficient butyrate-producing capacity in the gut microbiome of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome patients is associated with fatigue symptoms

People with Myalgic Encephalomyelitis / Chronic Fatigue Syndrome have a deficit in the butyrate-producing capacity of the gut microbiome. The relationships observed among symptom severity and gut microbiome disturbances suggests a causal linkage and support research into interventions that boost butyrate production.