Niacin.io is an independent research project investigating why nicotinic acid — specifically nicotinic acid, not niacinamide or other NAD+ precursors — appears to help autoimmune conditions.
The site curates peer-reviewed research, structures it as a knowledge graph, and presents synthesis through pathway pages that follow evidence from receptor to condition.
What this is not
- Not medical advice
- Not affiliated with any supplement company
- Not a clinical recommendation
Contribute
Know a relevant study we're missing? Found an error? Have a supplier to recommend?
- Submit a supplier for the sourcing directory
- The full research graph is available at /api/graph
- Evidence gaps are identified at /api/graph/gaps
How it works
All content lives as markdown files with structured YAML frontmatter. At boot, the application ingests these into Postgres, building a relational knowledge graph of studies, mechanisms, conditions, and pathways. The database is derived — blow it away and rebuild from markdown in seconds.
The API layer makes the graph queryable: filter studies, trace connections between mechanisms and conditions, and identify where evidence is thin.