The GPR109A receptor and its agonists (niacin and butyrate) have anti-inflammatory actions in the skin, gut and retina. For Parkinson's disease, niacin supplementation may have 3 benefits: lower inflammation via GPR109A-related mechanisms, increase dopamine production in brain by supplying NADPH and boosting mitochondrial functions by increasing the NAD/NADH ratio.
Most "niacin" products are niacinamide. If you want the form discussed in this research, look for nicotinic acid specifically.
Direct-buy option with a featured coupon code. Use the code below at checkout for the best visible discount path.
Use at checkout for 10% off.
Shop PureBulk →Pure nicotinic acid powder. No fillers, flexible dosing. This is the form studied in the GPR109A and lipid metabolism literature — not niacinamide.
View on Amazon →Smaller quantity for trying nicotinic acid. Same pure form, lower commitment.
View on Amazon →Niacin.io may earn from qualifying purchases.