This research used stable isotope tracing and microbiota-depleted mice to reveal that salvage NAD+ precursor supplements like nicotinamide (NAM) and nicotinamide ribose (NMR) don't actually boost NAD+, but depend on bacteria to first convert them into nicotinic acid. And that the resulting nicotinic acid is the converts to NAD+ via the Preiss Handler pathway.
Most "niacin" products are niacinamide. If you want the form discussed in this research, look for nicotinic acid specifically.
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Shop PureBulk →Pure nicotinic acid powder. No fillers, flexible dosing. This is the form studied in the GPR109A and lipid metabolism literature — not niacinamide.
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